Kazakevich R L, Shamraĭ L M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(2):207-10.
The authors describe the clinical traits of myeloradiculopolyneuritis (2 cases) and encephalopolyneuritis (1 case) developing 2--3 weeks following acute poisoning by chlorofos. Along with a distinct toxic polyneuritic syndrome there were also signs of pathology in the spinal cord and brain, as well as in the internal organs in the forms of toxic hepatitis and nephritis. The report contains data indicating a protracted development of the pathology, its direct dependence upon the depth of intoxication and disordered consciousness in the acute period. The authors express the opinion that in the described pathology there may be autoallergic mechanisms in the formation of myeloradiculopolyneuritis and encephalopolyneuritis following poisoning by chlorofos.
作者描述了在急性敌百虫中毒后2 - 3周发生的脊髓神经根多神经炎(2例)和脑多神经炎(1例)的临床特征。除了明显的中毒性多神经病变综合征外,还有脊髓、脑以及内脏器官出现病变的迹象,表现为中毒性肝炎和肾炎。该报告包含的数据表明,病变呈迁延性发展,直接取决于急性期中毒的深度和意识障碍情况。作者认为,在所描述的病变中,敌百虫中毒后形成脊髓神经根多神经炎和脑多神经炎可能存在自身免疫机制。