[Changes in the nervous system in acute oral chlorophos poisoning (clinical and pathomorphologic findings)].

In 136 patients with acute peroral poisoning by chlorofos with a light, moderate and severe degree there were symptoms of muscarine-nicotinelike action in the early periods of intoxication. In the postintoxicational period polyneuritis and astheno-vegetative syndromes could develop. There were also pathomorphological changes in the different parts of the nervous system detected in autopsy cases and characterized by perivascular and parenchymatous swelling and changes of the nervous cells of the brain and spinal cord of the type of acute disturbances. In some of the nervous cells there was a lysis of the cellular body and nucleus.