Siemkowicz E, Christiansen I, Sorensen S C
Acta Neurol Scand. 1977 Feb;55(2):137-44. doi: 10.1111/j.1600-0404.1977.tb05634.x.
The purpose of this study was to measure the changes in potassium concentration in human cisternal cerebrospinal fluid following successful resuscitation after cardiac arrest. We also wished to examine whether or not changes in potassium concentration in the cisternal cerebrospinal fluid could be correlated to the ability to regain normal cerebral function. 41 patients were studied, of whom 20 regained consciousness and 21 did not. In those who did not regain consciousness there was a significant increase in the potassium concentration found in samples obtained between 40 and 50 min, and between 50 and 60 min after cardiac arrest. The potassium concentration decreased to normal values during the following hours. Lumbar spinal fluid did not reflect the changes in cisternal fluid. The results suggest that the potassium concentration of cisternal cerebrospinal fluid, obtained soon after cardiac arrest, might give an indication of the degree of cerebral damage caused by cardiac arrest.
本研究的目的是测量心脏骤停成功复苏后人体枕大池脑脊液中钾浓度的变化。我们还希望研究枕大池脑脊液中钾浓度的变化是否与恢复正常脑功能的能力相关。对41例患者进行了研究，其中20例恢复了意识，21例未恢复意识。在未恢复意识的患者中，心脏骤停后40至50分钟以及50至60分钟采集的样本中钾浓度显著升高。在随后的几个小时内，钾浓度降至正常水平。腰椎脑脊液并未反映枕大池脑脊液的变化。结果表明，心脏骤停后不久采集的枕大池脑脊液中的钾浓度可能提示心脏骤停所致脑损伤的程度。
