Seki K, Makimura N, Mitsui C, Nagata I
Department of Obstetrics and Gynecology, National Defense Medical College, Saitama, Japan.
Obstet Gynecol. 1993 Feb;81(2):189-90.
To measure osteocalcin levels in fetal and maternal blood.
Osteocalcin was measured by radioimmunoassay in paired maternal and umbilical venous and arterial blood obtained at term deliveries.
Umbilical venous osteocalcin levels (mean +/- standard deviation) were significantly higher than arterial levels (10.28 +/- 4.99 versus 3.85 +/- 2.27 micrograms/L). Umbilical venous but not arterial levels of osteocalcin were significantly higher than maternal values (2.54 +/- 1.19 micrograms/L).
Higher osteocalcin levels in umbilical venous blood than in umbilical arterial blood suggest that the placenta may be the main source of osteocalcin in late fetal life.
测量胎儿和母体血液中的骨钙素水平。
采用放射免疫分析法,对足月分娩时采集的配对母体、脐静脉和动脉血中的骨钙素进行测量。
脐静脉骨钙素水平(均值±标准差)显著高于动脉水平(分别为10.28±4.99微克/升和3.85±2.27微克/升)。脐静脉而非动脉的骨钙素水平显著高于母体水平(2.54±1.19微克/升)。
脐静脉血中骨钙素水平高于脐动脉血,提示胎盘可能是胎儿晚期骨钙素的主要来源。