Walter T, Hertrampf E, Pizarro F, Olivares M, Llaguno S, Letelier A, Vega V, Stekel A
Hematology Unit, Universidad de Chile, Santiago.
Am J Clin Nutr. 1993 Feb;57(2):190-4. doi: 10.1093/ajcn/57.2.190.
The Chilean School Lunch program, which serves one million children nationwide, was supplied with three 10-g cookies fortified with 6% bovine hemoglobin concentrate, designed to provide 1 mg bioavailable iron per day. A survey of 1000 children was performed after 3 y. Significant differences in hemoglobin concentrations were found in the children from the fortified vs the nonfortified province (P < 0.01). Low serum ferritin values were also significantly more prevalent in the nonfortified group. The effect was evident despite the very low prevalence of anemia in both the fortified and the unfortified school groups. Heme-iron-fortified cookies are a feasible and effective way to improve the iron status of school-age children. In regions of high prevalence of iron-deficiency anemia, the effect of a heme-fortified cookie program should be even more important.
智利学校午餐计划为全国100万儿童提供服务，该计划供应了三种10克的饼干，这些饼干添加了6%的牛血红蛋白浓缩物，旨在每天提供1毫克可生物利用的铁。3年后对1000名儿童进行了一项调查。在食用强化饼干的省份和未食用强化饼干的省份的儿童中，血红蛋白浓度存在显著差异（P<0.01）。低血清铁蛋白值在未食用强化饼干的组中也明显更为普遍。尽管在强化和未强化的学校群体中贫血患病率都很低，但这种效果仍然很明显。血红素铁强化饼干是改善学龄儿童铁营养状况的一种可行且有效的方法。在缺铁性贫血高发地区，血红素强化饼干计划的效果应该会更加显著。
