Kambe F, Tsukahara S, Kato T, Seo H
Department of Endocrinology and Metabolism, Nagoya University, Japan.
Biochim Biophys Acta. 1993 Jan 23;1171(3):307-10. doi: 10.1016/0167-4781(93)90071-k.
The cDNA encoding a rat Oct-1 POU-domain was cloned by the reverse transcription-polymerase chain reaction method and subsequently Oct-1 mRNA expression was investigated. Our results show that the POU-domain of Oct-1 has been highly conserved during vertebrate evolution and that Oct-1 mRNA is widely expressed in various organs of adult rat.
通过逆转录-聚合酶链反应方法克隆了编码大鼠Oct-1 POU结构域的cDNA,随后对Oct-1 mRNA表达进行了研究。我们的结果表明,Oct-1的POU结构域在脊椎动物进化过程中高度保守,并且Oct-1 mRNA在成年大鼠的各种器官中广泛表达。