Thompson J S
Omaha Veterans Administration Medical Center, Nebraska.
Surg Gynecol Obstet. 1993 Jan;176(1):89-101.
None of the current surgical alternatives for the short bowel syndrome is sufficiently safe and effective to be used routinely. Surgical therapy should be considered only in selected patients to achieve specific results. Patients with dilated intestinal segments and stasis may benefit from intestinal tapering and lengthening. The results of intestinal transplantation in animals have improved and justify clinical attempts, but recent experience in humans has been disappointing. Growing neomucosa has not been shown to increase absorption, but the patching technique may be useful in preserving intestinal length. Patients with sufficient absorptive area but rapid transit may benefit from colon interposition or intestinal valves. Thus, the surgical emphasis should continue to be prevention of intestinal resection and conservation of intestinal length when resection is required.
目前针对短肠综合征的手术替代方案,没有一种足够安全有效到可以常规使用。手术治疗仅应在选定的患者中考虑,以实现特定的效果。肠道扩张和淤滞的患者可能从肠道减径和延长术中获益。动物肠道移植的结果有所改善,值得进行临床尝试,但近期人类的经验却令人失望。新黏膜生长尚未被证明能增加吸收,但补片技术可能有助于保留肠道长度。吸收面积足够但转运过快的患者可能从结肠间置术或肠瓣膜术中获益。因此,手术重点应继续放在预防肠道切除上,并且在需要切除时保留肠道长度。