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甲苯咪唑治疗猪带绦虫病和牛带绦虫病。

Mebendazole in the treatment of taeniasis solium and taeniasis saginata.

作者信息

Chavarria A P, Villarejos V M, Zeledón R

出版信息

Am J Trop Med Hyg. 1977 Jan;26(1):118-20. doi: 10.4269/ajtmh.1977.26.118.

DOI:10.4269/ajtmh.1977.26.118
PMID:842772
Abstract

A study was made of the effect on taeniasis of mebendazole, a drug known to be highly active against a variety of nematode species parasitic in humans. Thirty-seven patients infected with Taenia solium and four with Taenia saginata, some of whom had concomitant nematode infections, were treated with one of three dosages for 3 to 6 days. Within 48 hours of treatment most patients had eliminated long chains of intact, but apparently lifeless, proglottids. Assessment of results was made by monthly post-treatment observations for 4 to 5 months. The optimum effective dose of mebendazole appears to be 300 mg twice daily for 3 days.

摘要

进行了一项关于甲苯达唑对绦虫病影响的研究,甲苯达唑是一种已知对寄生于人体的多种线虫种类具有高效活性的药物。37名感染猪带绦虫的患者和4名感染牛带绦虫的患者,其中一些患者同时伴有线虫感染,接受了三种剂量之一的治疗,为期3至6天。在治疗后48小时内,大多数患者排出了长串完整但显然无活力的节片。通过治疗后4至5个月每月的观察来评估结果。甲苯达唑的最佳有效剂量似乎是每日两次,每次300毫克,共3天。

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