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在菲律宾某流行地区使用甲苯达唑治疗牛带绦虫病。

The use of mebendazole in the treatment of Taenia saginata taeniasis in an endemic area in the Philippines.

作者信息

Arambulo P V, Cabrera B D, Cabrera M G

出版信息

Acta Trop. 1978 Sep;35(3):281-6.

PMID:31782
Abstract

The successful treatment of Taenia saginata taeniasis with mebendazole is herein reported. 41 subjects ascertained to have taeniasis based on the history of passage of gravid segments and positivity for Taenia egg were treated with 300 mg mebendazole b.i.d. for 3 days without need for fasting. No side-effects were observed. The drug acts as a taeniacide. The worms were expelled either as degenerated boluses or fragmented segments on the 2nd to the 4th day (Mean: 2.4 days) after the initial dose. 33 (84.6%) of the 41 subjects expelled the worm. A follow-up of all the subjects 2--3 months after treatment revealed that all those who expelled the worm following treatment and 6 of those who did not were negative for both Taenia egg and gravid segment, or a cure rate of 95%.

摘要

本文报道了用甲苯咪唑成功治疗牛肉绦虫病的情况。41名根据孕节排出史及牛肉绦虫卵阳性确诊为绦虫病的患者,接受了300mg甲苯咪唑每日2次、共3天的治疗,无需禁食。未观察到副作用。该药物起杀绦虫作用。在首剂用药后的第2至4天(平均2.4天),虫体以退化的团块或破碎的节片形式排出。41名患者中有33名(84.6%)排出了虫体。对所有患者在治疗后2至3个月进行随访发现,所有治疗后排出虫体的患者以及6名未排出虫体的患者,其牛肉绦虫卵和孕节均为阴性,治愈率为95%。

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