Conejo-Mir J S, Camacho F, Ríos J J, González-Cámpora R
Medical Surgical Dermatology and Venereology Department, V. Macarena University Hospital, Faculty of Medicine, Seville, Spain.
Dermatology. 1993;186(2):149-52. doi: 10.1159/000247327.
A 45-year-old male, with a history of malignant melanoma on the thorax excised 4 years ago, presented a sudden eruption of more than 300 pigmented lesions. Fifteen excisions of tumors in different stages were carried out on four different dates. Dermatopathological examinations revealed features of primary as well as metastatic malignant melanomas. We suggest that besides the extensive dissemination there was also an activation of the resting melanocytes, that led to the formation of multiple primary melanomas.
一名45岁男性,4年前胸部恶性黑色素瘤切除术后,突然出现300多个色素沉着病变。在四个不同日期对不同阶段的肿瘤进行了15次切除。皮肤病理检查显示原发性和转移性恶性黑色素瘤的特征。我们认为,除了广泛播散外,静止的黑素细胞也被激活,导致了多发性原发性黑色素瘤的形成。