Parodi A, Semino M, Gallo R, Rebora A
Department of Dermatology, University of Genoa, Italy.
Dermatology. 1993;186(2):155-7. doi: 10.1159/000247329.
Two patients with classic Kaposi sarcoma developed bullous lesions and pemphigus-like 'anti-intercellular-substance' antibodies when treated with interferon-alpha (IFN-alpha). In one of them direct immunofluorescence was consistent with pemphigus/pemphigoid features. The immunoprecipitation test showed no specific bands. The mechanism by which IFN-alpha may induce the production of anti-intercellular-substance antibodies is discussed.
