Dennis J S, Kruger J M, Mullaney T P
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
J Am Vet Med Assoc. 1993 Jan 15;202(2):313-8.
Lymphocytic/plasmacytic colitis was diagnosed in 14 cats during a 5-year period. Purebred cats were affected significantly (P < 0.001) more often than were nonpurebred cats. Six cats were male and 8 were female. Mean age at onset of clinical signs was 5.1 years (range, 0.5 to 9 years). Hematochezia, observed in 13 cats, was the most commonly reported sign; diarrhea was reported in 11 cats. Mildly high serum alanine transaminase activity and hypokalemia were frequent biochemical abnormalities. Campylobacter sp was cultured from the feces of 1 cat. On endoscopic examination, petechia and hyperemia of the colonic mucosa were detected in 7 of 8 cats. Cats were initially treated with dietary management alone or with a combination of dietary and pharmacologic management. Clinical signs in 7 of 11 treated cats completely resolved, whereas signs in 3 cats were considered improved. One cat was euthanatized when an inadequate response to treatment was observed. Most cats were eventually maintained on dietary management alone.
在5年期间，14只猫被诊断为淋巴细胞性/浆细胞性结肠炎。纯种猫比非纯种猫受影响的频率显著更高（P < 0.001）。6只为雄性猫，8只为雌性猫。出现临床症状时的平均年龄为5.1岁（范围为0.5至9岁）。13只猫出现便血，这是最常报告的症状；11只猫有腹泻症状。血清丙氨酸转氨酶活性轻度升高和低钾血症是常见的生化异常。从1只猫的粪便中培养出弯曲杆菌属。在内镜检查中，8只猫中有7只检测到结肠黏膜瘀点和充血。猫最初仅接受饮食管理或饮食与药物管理相结合的治疗。11只接受治疗的猫中有7只的临床症状完全缓解，而3只猫的症状有所改善。当观察到对治疗反应不佳时，1只猫被安乐死。大多数猫最终仅依靠饮食管理维持。
