Su J
Department of Obstetrics and Gynecology, Hepei Medical University, China.
Nihon Sanka Fujinka Gakkai Zasshi. 1993 Feb;45(2):141-7.
From 1985 to 1989, analysis of the umbilical cord blood gas in 546 cases of cesarean section delivery under spinal anesthesia was carried out to evaluate its relationship with neonatal asphyxia, and the following results were obtained. (1) The UApH of a normal newborn with an Apgar score > 7 was 7.28 +/- 0.04. Acidosis occurred in 33.3% of the infants born with an Apgar score < 7, but the incidence was only 3.9% in those with an Apgar score > 7. Sixteen% of the acidosis was metabolic and 84% belonged to the mixed type. The UApH and Apgar scores were most significantly related. (2) The abnormal UVpH was 4.9% (< M - 2SD). (3) There was no significant difference in UApH between cesarean section performed before and after the onset of labor. (4) The short term morbidity included: one death, 2 cases of convulsions, 2 cases of cerebral edema, and one case of periventricular leukomalacia. (5) The long term morbidity in the 29 cases referred to NICU included: 18 cases of normal growth, 2 cases of severe cerebral palsy, 3 cases of mild cerebral palsy, and 6 cases of mental retardation. (6) In view of the long term morbidity of the newborn, as seen in the correlation between the Apgar score and UApH, it was considered that, the critical points in neonatal asphyxia were Apgar score < or = 3 and UApH < 7.10. My results suggested that the umbilical cord blood gas analysis was helpful for the diagnosis of neonatal asphyxia, and the prognosis of the newborn.
1985年至1989年,对546例腰麻下剖宫产分娩的脐带血气进行分析,以评估其与新生儿窒息的关系,结果如下:(1)Apgar评分>7的正常新生儿脐动脉血pH值为7.28±0.04。Apgar评分<7的新生儿中33.3%发生酸中毒,但Apgar评分>7的新生儿中发生率仅为3.9%。16%的酸中毒为代谢性,84%为混合型。脐动脉血pH值与Apgar评分相关性最为显著。(2)脐动脉血pH值异常者为4.9%(<M-2SD)。(3)临产前后剖宫产的脐动脉血pH值无显著差异。(4)短期发病率包括:1例死亡、2例惊厥、2例脑水肿和1例脑室周围白质软化。(5)转入新生儿重症监护病房(NICU)的29例患儿的长期发病率包括:18例生长正常、2例重度脑瘫、3例轻度脑瘫和6例智力低下。(6)鉴于新生儿的长期发病率,从Apgar评分与脐动脉血pH值的相关性来看,认为新生儿窒息的临界点为Apgar评分≤3且脐动脉血pH值<7.10。我的结果表明,脐带血气分析有助于新生儿窒息的诊断及新生儿的预后评估。