Suratt P M, Winn W C, Brody A R, Bolton W K, Giles R D
Am Rev Respir Dis. 1977 Mar;115(3):521-9. doi: 10.1164/arrd.1977.115.3.521.
Four men developed silicosis after sandblasting tombstones for an average of 35 months; 3 of them died an average of 59 months after their first exposure to sandblasting. Lung tissue demonstrated noncaseating granulomas and silicotic nodules involving small arteries and veins in 3 patients and alveolar proteinosis in 2. X-ray energy spectrometry showed primarily elemental silicon in the lung parenchyma. One patient developed lupus erythematosus and another focal glomerulonephritis. Two developed pneumothorax. None had cultural or morphologic evidence of tuberculosis. Pulmonary function studies in all 4 patients revealed a restrictive pattern. Industrial investigations revealed that the patients wore inadequate personal protection equipment and were exposed to 5 times the threshold limit value for respirable silica.
四名男子在喷砂处理墓碑平均35个月后患上矽肺病；其中3人在首次接触喷砂处理平均59个月后死亡。肺部组织显示，3例患者出现非干酪性肉芽肿和累及小动脉和静脉的矽结节，2例出现肺泡蛋白沉积症。X射线能谱分析显示肺实质主要为元素硅。一名患者患上红斑狼疮，另一名患上局灶性肾小球肾炎。两人出现气胸。所有人均无结核病的培养或形态学证据。所有4例患者的肺功能研究均显示为限制性模式。工业调查发现，这些患者使用的个人防护装备不足，且接触的可吸入二氧化硅超过阈限值5倍。
