Jortani S A, Poklis A
Department of Pathology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0597.
J Anal Toxicol. 1993 Jan-Feb;17(1):31-3. doi: 10.1093/jat/17.1.31.
The Syva ETS is an automated system designed for analysis of drugs of abuse in urine. Recently, the Syva Company has upgraded this system to the ETS Plus, which is capable of analyzing ethanol in urine, serum, or plasma. We evaluated the new ETS Plus for urine screening of barbiturates, benzodiazepines, cocaine metabolite, opiates, and phencyclidine. Results of 505 patient sample assays obtained by ETS Plus were compared with those of ETS. There were only four discrepant results which had absorbance rates close to the low calibrator cutoff values. The within-run precision of the ETS Plus Ethyl Alcohol Assay yielded a CV of 2.6% at a target value of 1.00 g/L (1.06 +/- 0.03 g/L, n = 32) and a CV of 3.2% at a target value of 0.40 g/L (0.42 +/- 0.01 g/L, n = 30). The linear regression analysis of 30 patient serum ethanol results by the ETS Plus and by gas chromatography yielded y = 0.939 x + 0.03 g/L. The software modifications in the new ETS Plus allow the accurate quantitation of ethanol in serum and reliable detection of drugs of abuse within the same batch.
Syva ETS是一种用于分析尿液中滥用药物的自动化系统。最近，Syva公司已将该系统升级为ETS Plus，它能够分析尿液、血清或血浆中的乙醇。我们评估了新的ETS Plus用于尿液中巴比妥类药物、苯二氮卓类药物、可卡因代谢物、阿片类药物和苯环己哌啶的筛查。将ETS Plus对505份患者样本检测的结果与ETS的结果进行了比较。仅有4个差异结果，其吸光度率接近低校准物临界值。ETS Plus乙醇检测的批内精密度在目标值为1.00 g/L（1.06±0.03 g/L，n = 32）时CV为2.6%，在目标值为0.40 g/L（0.42±0.01 g/L，n = 30）时CV为3.2%。对30份患者血清乙醇结果用ETS Plus和气相色谱法进行线性回归分析，得出y = 0.939x + 0.03 g/L。新的ETS Plus中的软件改进使得能够准确定量血清中的乙醇，并能在同一批次内可靠检测滥用药物。
