Morales M A, Pineda J A, Leal M, Pino R, Torronteras R, Sánchez-Quijano A, Lissen E
Departamento de Medicina Interna, Hospital Universitario Virgen del Rocío, Sevilla.
Med Clin (Barc). 1993 Jan 16;100(2):50-2.
The finding of an important proportion of cases of hepatitis C without previous contact with blood or hemoderivates has led to suspect that there may be other routes of transmission among which sexual transmission may be found.
The presence of antibodies against the hepatitis C virus (anti-HCV) and the association of this infection with certain epidemiologic parameters and sexual practice was determined in 184 homosexual males with no other risk factors for virasis of intravenous transmission. Moreover, the prevalence of anti-HCV was evaluated in 210 voluntary blood donors. Every homosexual was surveyed on sexual practice and the first serum sample available of each of these patients was analyzed for anti-HVC and anti-HIV-1.
Twenty-two homosexual (12%) were anti-HCV positive while only one (0.5%) of the control was positive for this marker (p < 0.0001). Thirty-six cases (19%) were anti-HIV positive (none of the controls). No statistical association was found between both serologic markers or between the presence of anti-HCV and the epidemiologic parameters evaluated.
Homosexuals constitute a risk group for hepatitis C virus infection although the sexual route is probably not effective for transmission of this entity.
发现相当比例的丙型肝炎病例之前并未接触过血液或血液制品，这使得人们怀疑可能存在其他传播途径，其中可能包括性传播。
对184名无静脉注射传播病毒其他危险因素的同性恋男性进行了丙型肝炎病毒抗体（抗-HCV）检测，并确定了这种感染与某些流行病学参数及性行为的关联。此外，对210名自愿献血者的抗-HCV患病率进行了评估。对每名同性恋者的性行为进行了调查，并对这些患者的首份可用血清样本进行了抗-HCV和抗-HIV-1分析。
22名同性恋者（12%）抗-HCV呈阳性，而对照组中只有1人（0.5%）该指标呈阳性（p<0.0001）。36例（19%）抗-HIV呈阳性（对照组均为阴性）。在两种血清学标志物之间，或抗-HCV的存在与所评估的流行病学参数之间均未发现统计学关联。
同性恋者是丙型肝炎病毒感染的高危人群，尽管性传播途径可能并非传播该病毒的有效途径。
