Weber D M, Wang Y, Korosec F R, Mistretta C A
Department of Medical Physics, University of Wisconsin-Madison.
Magn Reson Med. 1993 Feb;29(2):216-25. doi: 10.1002/mrm.1910290210.
Thick slab two-dimensional phase contrast (2D PC) angiography provides a large amount of anatomical information in a short acquisition time. Quantitative velocity information is, however, destroyed by the necessary projection dephasing gradient. We present a 2D PC acquisition scheme which retains quantitative velocity information in a thick slab acquisition. A thick slab acquisition produces an image which is a projection through an entire vessel. Accurate velocity measurements must take into account the intravoxel phase cancellation caused by a distribution of velocities within the vessel. In addition to the description of the data acquisition scheme, we outline a method for determining the mean velocity within a vessel having a laminar flow distribution. It is shown that without the consideration for intravoxel phase cancellation, the mean velocity measurement from thick slab images overestimates the true mean velocity by 10%.
厚层二维相位对比(2D PC)血管造影术在短采集时间内可提供大量解剖学信息。然而,由于必要的投影去相位梯度,定量速度信息被破坏。我们提出了一种2D PC采集方案,该方案在厚层采集中保留了定量速度信息。厚层采集产生的图像是通过整个血管的投影。准确的速度测量必须考虑血管内速度分布引起的体素内相位抵消。除了对数据采集方案的描述外,我们还概述了一种确定具有层流分布的血管内平均速度的方法。结果表明,若不考虑体素内相位抵消,厚层图像的平均速度测量值会高估真实平均速度10%。