皮肤电传导反应（SCR）习惯化测试，作为一种焦虑的基本模型，是评估某些药物致焦虑活性的一种工具。

Skin conductance reaction (SCR)-habituation test, an elementary model of anxiety as a tool to assess anxiogenic activities of some drugs.

Quermonne M A, Nammathao B, Louchahi-Raoul J, Marcy R

Department of Pharmacology, University of Caen, France.

Prog Neuropsychopharmacol Biol Psychiatry. 1993 Mar;17(2):311-8. doi: 10.1016/0278-5846(93)90050-3.

Abstract

The SCR-habituation test, used as a tool to detect an anxiolytic activity, is applied to the study of several anxiogenic drugs. This test is based on the measure of the SCR-extinction time (i.e. habituation) got by the way of an iterative photostimulus. 2. 8 anxiogenic compounds are tested. They delay significantly and quantitatively the SCR habituation. 3. Specificity, sensitivity and quantifying values of the test are considered in order to propose the use of the SCR-habituation test in the investigation of putative anxiogenic compounds.

摘要

皮肤电反应（SCR）习惯化测试被用作检测抗焦虑活性的工具，应用于多种致焦虑药物的研究。该测试基于通过反复光刺激获得的SCR消退时间（即习惯化）的测量。2. 对8种致焦虑化合物进行了测试。它们显著且定量地延迟了SCR习惯化。3. 考虑该测试的特异性、敏感性和量化值，以便提出在推定的致焦虑化合物研究中使用SCR习惯化测试。