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静脉曲张突然大量出血的处理

Management of sudden profuse bleeding from varicose veins.

作者信息

McCarthy W J, Dann C, Pearce W H, Yao J S

机构信息

Division of Vascular Surgery, Chicago, IL 60611.

出版信息

Surgery. 1993 Feb;113(2):178-83.

PMID:8430366
Abstract

Varicose vein bleeding of the lower extremities is an unusual but pressing indication for treatment and can be lethal. This series reviews operative and injection treatment of such veins in patients with bleeding. During a 49-month period 14 patients (eight men and six women) with a mean age of 62.1 years (range, 23 to 93 years) were seen after venous bleeding related to varicosities of the lower extremity. They described between one and five episodes of bleeding (mean, 2.4), but only one patient required transfusion. The site of bleeding was the lower calf or foot in 11 and affected the thigh in three patients. One was in the third trimester of pregnancy. Nine patients had lesions involving clustered small 1 mm or less diameter varicose veins, whereas five had large diffuse varicose vein formation. None had evidence of coagulopathy, and the inciting episode was either unknown or related to minor trauma. Treatment of eight patients with small-diameter veins was instituted with 0.2% sodium tetradecyl injection with a 30-gauge needle, thrombosing veins within 5 cm of the bleeding focus. A total of 13 ml solution (1.0 to 27 ml) per patient was used during two or three treatment periods (mean, 2.5 treatment periods) spaced 2 weeks apart. Six patients were treated by means of standard vein-stripping techniques or local branch removal at the bleeding site. Effective thrombosis was achieved in all eight patients with small (less than 1 mm) varicose veins treated with sclerosis. In five patients who underwent surgery there was effective resolution of the hemorrhage. One patient with small-diameter varicose veins clustered about the ankle underwent operative treatment and had venous stasis ulceration requiring compression dressings for healing. In all 14 cases control of bleeding was obtained, with follow-up to 49 months (mean, 21.3 months); one had rebleeding from a site 32 cm remote from the original injected area 11 months after treatment. Bleeding from small-diameter varicose veins of the lower extremity can be controlled effectively by sclerosing techniques with sodium tetradecyl. Larger veins are managed with operative removal. Combining these techniques provides efficient management of often-elderly patients, many in an outpatient setting.

摘要

下肢静脉曲张出血是一种不常见但亟待治疗的情况,可能会危及生命。本系列回顾了此类出血患者的手术及注射治疗。在49个月期间,有14名患者(8名男性和6名女性)因下肢静脉曲张相关的静脉出血前来就诊,平均年龄为62.1岁(范围23至93岁)。他们描述有1至5次出血发作(平均2.4次),但只有1名患者需要输血。出血部位在小腿下部或足部的有11例,累及大腿的有3例。其中1例处于妊娠晚期。9例患者的病变涉及直径1毫米及以下的成簇小静脉曲张,而5例有大的弥漫性静脉曲张形成。均无凝血功能障碍的证据,诱发事件不明或与轻微创伤有关。8例小直径静脉患者采用30号针头注射0.2%十四烷基硫酸钠进行治疗,使距出血灶5厘米内的静脉形成血栓。在间隔2周的两到三个治疗周期(平均2.5个治疗周期)中,每位患者共使用13毫升溶液(1.0至27毫升)。6例患者采用标准静脉剥脱技术或在出血部位局部切除分支进行治疗。所有8例接受硬化治疗的小(小于1毫米)静脉曲张患者均实现了有效血栓形成。5例接受手术的患者出血得到有效解决。1例踝关节周围小直径静脉曲张成簇的患者接受了手术治疗,出现静脉淤滞性溃疡,需要加压包扎才能愈合。14例患者均实现了出血控制,随访至49个月(平均21.3个月);1例在治疗11个月后,在距原注射部位32厘米处再次出血。下肢小直径静脉曲张出血可通过十四烷基硫酸钠硬化技术有效控制。较大的静脉则通过手术切除处理。结合这些技术可为老年患者提供有效的治疗管理,许多患者可在门诊进行治疗。

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