Suttorp-Schulten M S, Luyendijk L, van Dam A P, de Keizer R J, Baarsma G S, Bos P J, Rothova A
Netherlands Ophthalmic Research Institute, Amsterdam.
Am J Ophthalmol. 1993 Feb 15;115(2):149-53. doi: 10.1016/s0002-9394(14)73917-0.
Two patients in whom ocular Lyme disease was suspected and who had antibodies to Borrelia burgdorferi developed birdshot chorioretinopathy and carried the HLA-A29 antigen. In a series of 11 patients with birdshot chorioretinopathy who carried the HLA-A29 antigen, three patients had antibodies against B. burgdorferi as determined by either immunofluorescence assay, enzyme-linked immunosorbent assay, Western blot analysis, or a combination of these tests. Further studies will be necessary to evaluate whether this is a false-positive reaction or whether B. burgdorferi has a causative role in the pathogenesis of birdshot chorioretinopathy.
两名疑似患有眼部莱姆病且具有抗伯氏疏螺旋体抗体的患者发生了鸟枪弹样脉络膜视网膜病变，并携带HLA - A29抗原。在一组11例携带HLA - A29抗原的鸟枪弹样脉络膜视网膜病变患者中，通过免疫荧光试验、酶联免疫吸附测定、蛋白质印迹分析或这些试验的组合确定，有3例患者具有抗伯氏疏螺旋体抗体。有必要进行进一步研究，以评估这是假阳性反应，还是伯氏疏螺旋体在鸟枪弹样脉络膜视网膜病变的发病机制中起致病作用。
