Rosholm J U, Hallas J, Gram L F
Department of Clinical Pharmacology, Odense University, Denmark.
J Affect Disord. 1993 Jan;27(1):21-8. doi: 10.1016/0165-0327(93)90092-x.
A prescription database analysis was conducted to describe the users of antidepressants outside hospitals in the Odense area (207,000 inhabitants) during one year. In total, 1.62% (N = 3360) of the population used antidepressants. Women and users aged over 70 years constituted a disproportionately large part. Seventy-five percent of the patients used tricyclic antidepressants. The estimated daily doses for the tricyclic antidepressants were generally low, the third quartile being less than 100 mg daily. The low doses may be due to antidepressants being used on other indications than depression or that a considerable number of the patients are not given a sufficient dose.
进行了一项处方数据库分析，以描述欧登塞地区（20.7万居民）一年中在医院外使用抗抑郁药的人群。总体而言，1.62%（N = 3360）的人口使用抗抑郁药。女性和70岁以上的使用者占比过大。75%的患者使用三环类抗抑郁药。三环类抗抑郁药的估计日剂量普遍较低，第三四分位数低于每日100毫克。低剂量可能是由于抗抑郁药用于抑郁症以外的其他适应症，或者相当数量的患者未得到足够的剂量。
