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[血栓性血小板减少性紫癜治疗的变化与进展——治疗性血浆输注和血浆置换方案——日本和加拿大研究组的治疗结果]

[Changes and progress in the treatment of TTP--protocols of therapeutic plasma infusion and plasma exchange--therapeutic results by the Japanese and Canadian Study Groups].

作者信息

Ito K, Hattori A, Hirosawa S, Takamatsu J, Kakishita E, Fujimura K

机构信息

Department of Transfusion Medicine, Kyoto University Hospital.

出版信息

Nihon Rinsho. 1993 Jan;51(1):184-6.

PMID:8433516
Abstract

Plasma exchange (PE) and plasma infusion (PI) are effective in the treatment of TTP (thrombotic thrombocytopenic purpura). Comparison of PE and PI in the treatment of TTP was carried out by the Canadian Apheresis Study Group, which reported that PE was superior to PI. The Japanese TTP Study Group made a therapeutic protocol in which a smaller volume of Fresh frozen plasma (FFP) was used in the treatment with PI. The efficacy of PE and PI was similar. The results suggest that the volume of FFP necessary for effective treatment is not very large.

摘要

血浆置换(PE)和血浆输注(PI)在血栓性血小板减少性紫癜(TTP)的治疗中是有效的。加拿大血液分离研究小组对PE和PI治疗TTP进行了比较,该小组报告称PE优于PI。日本TTP研究小组制定了一种治疗方案,其中在PI治疗中使用较少量的新鲜冰冻血浆(FFP)。PE和PI的疗效相似。结果表明,有效治疗所需的FFP量不是很大。

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