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一种果蝇光感受器细胞特异性蛋白,钙光蛋白,可结合钙并含有一个亮氨酸拉链。

A Drosophila photoreceptor cell-specific protein, calphotin, binds calcium and contains a leucine zipper.

作者信息

Ballinger D G, Xue N, Harshman K D

机构信息

Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY.

出版信息

Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1536-40. doi: 10.1073/pnas.90.4.1536.

Abstract

The calphotin protein, encoded by the calphotin (cap) gene, is expressed in the soma and axons of all Drosophila photoreceptor cells. It is expressed early in photo-receptor cell development, at the time when cell-type decisions are being made. Expression of calphotin is not altered by the glass mutation, which blocks photoreceptor cell development. The calphotin protein binds calcium and contains a long C-terminal leucine zipper. Potential implications of these properties are discussed.

摘要

钙光蛋白(Calphotin)由钙光蛋白(cap)基因编码,在所有果蝇光感受器细胞的胞体和轴突中表达。它在光感受器细胞发育早期表达,即在进行细胞类型决定时表达。钙光蛋白的表达不受玻璃突变的影响,玻璃突变会阻断光感受器细胞的发育。钙光蛋白与钙结合,并含有一个长的C端亮氨酸拉链。文中讨论了这些特性的潜在影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b583/45909/49e60b161481/pnas01102-0408-a.jpg

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