Ballinger D G, Xue N, Harshman K D
Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY.
Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1536-40. doi: 10.1073/pnas.90.4.1536.
The calphotin protein, encoded by the calphotin (cap) gene, is expressed in the soma and axons of all Drosophila photoreceptor cells. It is expressed early in photo-receptor cell development, at the time when cell-type decisions are being made. Expression of calphotin is not altered by the glass mutation, which blocks photoreceptor cell development. The calphotin protein binds calcium and contains a long C-terminal leucine zipper. Potential implications of these properties are discussed.
钙光蛋白(Calphotin)由钙光蛋白(cap)基因编码,在所有果蝇光感受器细胞的胞体和轴突中表达。它在光感受器细胞发育早期表达,即在进行细胞类型决定时表达。钙光蛋白的表达不受玻璃突变的影响,玻璃突变会阻断光感受器细胞的发育。钙光蛋白与钙结合,并含有一个长的C端亮氨酸拉链。文中讨论了这些特性的潜在影响。