Marcus S, al-Moslih M, al-Tawil N G, Kassir Z A
Department of Microbiology, College of Medicine, University of Baghdad, Iraq.
Scand J Immunol. 1993 Feb;37(2):265-70. doi: 10.1111/j.1365-3083.1993.tb01765.x.
One hundred and seven patients with acute viral hepatitis (AVH) were studied prospectively regarding the viral aetiological agent HAV, HBV and NANB (by exclusion) using radioimmunoassay. Acute HAV infection occurred in 43 patients, and acute HBV infection in 34 patients, while HDS occurred in two patients only. Acute, presumably NANB, infection occurred in 28 patients. Ten out of 28 sera of patients with AHBV infection were positive for smooth muscle antibody by immunofluorescence. Important findings include: (1) presence of delta superinfection in the absence of HBsAg; (2) HBsAg as the only marker in two patients with AHBV infection; (3) concurrent presence of HBsAg and anti-HBsAg in three patients with AHBV infection.
采用放射免疫分析法对107例急性病毒性肝炎（AVH）患者进行前瞻性研究，以确定其病毒病原体为甲型肝炎病毒（HAV）、乙型肝炎病毒（HBV）及非甲非乙型肝炎病毒（NANB，通过排除法）。43例患者发生急性HAV感染，34例患者发生急性HBV感染，而仅2例患者发生丁型肝炎病毒（HDS）感染。28例患者发生急性（推测为NANB）感染。28例急性乙型肝炎病毒（AHBV）感染患者的血清中有10例通过免疫荧光检测平滑肌抗体呈阳性。重要发现包括：（1）在无乙肝表面抗原（HBsAg）的情况下存在丁型肝炎病毒重叠感染；（2）2例AHBV感染患者中HBsAg为唯一标志物；（3）3例AHBV感染患者中同时存在HBsAg和抗HBsAg。
