Lupret V, Negovetic L, Smiljanic D, Klanfar Z, Lambasa S
Department of Neurosurgery, Clinical Hospital, Sestre Milosrdnice, Zagreb, Croatia.
Acta Neurochir (Wien). 1993;120(1-2):33-9. doi: 10.1007/BF02001466.
Eleven patients with venous angiomas, 6 males and 5 females ranging in age from 4 to 58, are presented. Four patients presented with intracerebral haematoma and 3 patients had associated cavernous angioma, respectively. Patients with intracerebral haematoma had signs and symptoms due to the localization of the haematoma. The other patients presented with headache, seizures, vertigo, ataxia and mental disturbances. Pre-operative diagnosis was based on computerized tomography, magnetic resonance imaging and cerebral angiography. In 9 surgical cases it was confirmed by histopathological examination of operative specimens. After establishing the type, size and location of the lesion decision for operative treatment was made in nine cases, in four of them because of the presence of an intracerebral haematoma and in 5 of them due to severe disability. Eight of these 9 patients recovered completely and one improved. No severe cerebral oedema was encountered after converging medullary veins were excised and main draining veins partially coagulated. In this small series we encountered an unexpectedly large percentage of venous angiomas causing intracerebral haemorrhage which are commonly considered more benign than other vascular malformations. After reviewing previously reported cases of venous angiomas causing intracerebral haemorrhage and severe neurological deficit we think that the term "benign" is worth reconsidering. We propose a thorough examination of each case of venous angioma and the operative treatment when appropriate taking into account patients state and location of angioma.
本文报告了11例静脉血管瘤患者,其中男性6例,女性5例,年龄在4岁至58岁之间。4例患者出现脑内血肿,3例患者分别合并海绵状血管瘤。脑内血肿患者因血肿的定位而出现相应的体征和症状。其他患者表现为头痛、癫痫、眩晕、共济失调和精神障碍。术前诊断基于计算机断层扫描、磁共振成像和脑血管造影。9例手术病例经手术标本的组织病理学检查得以证实。在明确病变的类型、大小和位置后,9例患者决定接受手术治疗,其中4例是因为存在脑内血肿,5例是由于严重残疾。这9例患者中有8例完全康复,1例有所改善。在切除汇聚的髓静脉并部分凝固主要引流静脉后,未出现严重的脑水肿。在这个小样本系列中,我们发现导致脑内出血的静脉血管瘤比例出乎意料地高,而静脉血管瘤通常被认为比其他血管畸形更具良性。在回顾了先前报道的导致脑内出血和严重神经功能缺损的静脉血管瘤病例后,我们认为“良性”这个术语值得重新考虑。我们建议对每例静脉血管瘤病例进行全面检查,并在适当的时候根据患者的状态和血管瘤的位置考虑进行手术治疗。