Jiménez R A, Myerburg R J
University of Miami School of Medicine, Florida.
Cardiol Clin. 1993 Feb;11(1):1-9.
Sudden cardiac death continues to be a major clinical and public health problem. Prospective identification of patients at high risk for cardiac arrest is difficult, being limited by the large size of the population subgroups that contain the majority of victims of sudden cardiac death and by the time dependence of risk of sudden death. Pathophysiologically, sudden cardiac death can be viewed as an interaction between structural abnormalities of the heart, transient functional disturbances, and the specific electrophysiologic events responsible for fatal arrhythmias. Further understanding of the dynamics of high-risk populations and mechanisms of sudden death may lead to effective measures for control of risk.
心脏性猝死仍然是一个主要的临床和公共卫生问题。前瞻性识别心脏骤停高危患者很困难，这受到包含大多数心脏性猝死受害者的人群亚组规模庞大以及猝死风险的时间依赖性的限制。从病理生理学角度看，心脏性猝死可被视为心脏结构异常、短暂功能紊乱以及导致致命性心律失常的特定电生理事件之间的相互作用。进一步了解高危人群的动态变化和猝死机制可能会带来控制风险的有效措施。
