Laine T, Alvesalo L
Department of Orthodontics, Faculty of Dentistry, University of Kuopio, Finland.
Hum Biol. 1993 Feb;65(1):131-8.
Men with one extra X chromosome (47,XXY; Klinefelter syndrome) show a tendency to have a shallower but longer palate than normal (46,XY) men. The palate is also narrower than in 46,XY men. The mandible is clearly narrower but sagittally longer compared with the mandibles of 46,XY men. The present results indicate that the presence of one extra X chromosome in 47,XXY men is reflected in decreased growth of the maxilla transversely and vertically and of the mandible transversely. Increased length of the alveolar arches might be partly a compensation for the decreased width of the alveolar arch. This change might be associated with larger tooth sizes in 47,XXY men. Unbalanced appositional growth rather than disturbances in other orofacial growth mechanisms might be associated with the XXY sex chromosome pattern.
具有一条额外X染色体（47,XXY；克兰费尔特综合征）的男性相较于正常（46,XY）男性，其腭部往往更浅但更长。腭部也比46,XY男性的更窄。与46,XY男性的下颌骨相比，下颌骨明显更窄但矢状面更长。目前的结果表明，47,XXY男性中额外一条X染色体的存在反映在上颌骨横向和纵向以及下颌骨横向生长的减少。牙槽弓长度增加可能部分是对牙槽弓宽度减少的一种补偿。这种变化可能与47,XXY男性中更大的牙齿尺寸有关。不平衡的表面生长而非其他口面部生长机制的紊乱可能与XXY性染色体模式有关。
