Oshita S, Nakakimura K, Kaieda R, Murakawa T, Tamura H, Hiraoka I
Department of Anesthesiology, Yamaguchi University Hospital, Ube.
Masui. 1993 Feb;42(2):185-9.
The concept of Zadeh's fuzzy logistic controller was applied to control hypertension during anesthesia, and its clinical usefulness was examined in patients undergoing elective surgery. Arterial blood pressure was determined by use of an automatic blood pressure device. Nicardipine was used as hypotensive drug. Based on the fuzzy control rules, we developed state-action diagram so as to maintain systolic blood pressure at around 130 mmHg. Nicardipine was infused by using a digitally controlled infusion pump, and its infusion rate was changed according to this diagram. Although acute hypertension associated with endotracheal intubation was not significantly attenuated, hypertension associated with either skin incision or endotracheal extubation, where blood pressure increased slowly, was successfully controlled with our system. These results suggest that the application of the concept of fuzzy logistic controller is useful for treatment of hypertension during anesthesia, especially when blood pressure increases slowly.
扎德模糊逻辑控制器的概念被应用于麻醉期间的高血压控制，并在接受择期手术的患者中检验了其临床实用性。使用自动血压装置测定动脉血压。尼卡地平用作降压药物。基于模糊控制规则，我们绘制了状态-行动图，以便将收缩压维持在130 mmHg左右。使用数字控制输液泵输注尼卡地平，其输注速率根据该图进行改变。尽管与气管插管相关的急性高血压没有得到显著缓解，但与皮肤切口或气管拔管相关的高血压（血压缓慢升高）通过我们的系统成功得到了控制。这些结果表明，模糊逻辑控制器概念的应用对于麻醉期间高血压的治疗是有用的，尤其是在血压缓慢升高时。
