Bickel H, Cooper B, Wancata J
Abteilung für Epidemiologische Psychiatrie, Zentralinstitut für Seelische Gesundheit, Mannheim.
Nervenarzt. 1993 Jan;64(1):53-61.
As part of a survey conducted in six general-hospital departments of internal medicine, in the neighbouring cities of Mannheim and Ludwigshafen (total pop. 470,000), 626 patients in the age range 65 to 80 years, all admitted from private addresses, were screened by means of a standardized questionnaire (Cognitive and Affective Screening of the Elderly--'CASE'). All patients whose scores indicated possible mental abnormality, together with a proportion of those having normal scores, were then examined in greater detail, using the Clinical Psychiatric Interview. Following correction, the screening results indicated a frequency of 30.2% for clinically significant psychiatric disturbance, made up of 9.1% with organic mental disorders and 21.1% with functional mental illness only. These rates are considerably higher than could be expected on the basis of a field study of the background population. One year after hospital discharge, the numbers of deaths and of admissions to long-stay care were established for the whole sample, and in addition, individually matched sub-samples of 100 mentally ill and 100 mentally normal patients were reinvestigated. A second follow-up of the matched sub-samples was undertaken after a further interval of 5.6 years on average. The results of follow-up show that 75% of the identified cases ran a chronic or recurring course, while only a small proportion proved to be transient reactions to physical illness or hospital admission. In general, the psychiatrically ill patients had a relatively unfavourable outcome, even after the effects of age, physical disability and other relevant variables had been controlled for. When compared with the matched group of mentally normal patients, they manifested a 43% excess of mortality, and an increase of 157% in the risk for having to be admitted to long-stay care.
作为在曼海姆和路德维希港这两个相邻城市(总人口47万)的六家综合医院内科进行的一项调查的一部分,对626名年龄在65至80岁之间、均从私人住址入院的患者,通过标准化问卷(老年人认知与情感筛查——“CASE”)进行了筛查。然后,所有得分表明可能存在精神异常的患者,以及一部分得分正常的患者,使用临床精神科访谈进行了更详细的检查。校正后,筛查结果显示临床上显著的精神障碍发生率为30.2%,其中器质性精神障碍占9.1%,仅功能性精神疾病占21.1%。这些发生率远高于基于对背景人群的实地研究预期的发生率。出院一年后,确定了整个样本的死亡人数和长期护理入院人数,此外,对100名精神疾病患者和100名精神正常患者的个体匹配子样本进行了重新调查。在平均又经过5.6年的间隔后,对匹配子样本进行了第二次随访。随访结果显示,75%的确诊病例病程呈慢性或复发,而只有一小部分被证明是对身体疾病或入院的短暂反应。总体而言,即使在控制了年龄、身体残疾和其他相关变量的影响后,精神疾病患者的预后相对较差。与匹配的精神正常患者组相比,他们的死亡率高出43%,长期护理入院风险增加了157%。