Strong T H, Elliott J P, Radin T G
Phoenix Perinatal Associates, Division of Maternal-Fetal Medicine, Good Samaritan Regional Medical Center, Arizona.
Obstet Gynecol. 1993 Mar;81(3):409-11.
To evaluate the perinatal outcomes of fetuses born with non-coiled umbilical blood vessels.
We performed a prospective study of umbilical cords that lacked umbilical vascular coiling. The perinatal outcomes were compared with those of neonates born with coiled umbilical blood vessels.
Thirty-eight (4.3%) of 894 fetuses were born with non-coiled umbilical vessels. The non-coiled group had a significantly increased incidence of intrauterine death (P = .009), preterm delivery (P = .006), repetitive intrapartum fetal heart rate decelerations (P < .00005), operative delivery for fetal distress (P < .00005), meconium staining (P = .007), and anatomical-karyotypic abnormalities (P = .03).
Our findings suggest that the fetus with non-coiled (ie, straight) umbilical blood vessels is at increased risk for perinatal morbidity and mortality. Non-coiled umbilical vessels may represent a pathologic developmental process that places the fetus at risk. Moreover, absence of the normal coiled umbilical configuration may result in a cord that is structurally less able to resist external compressive forces.
评估出生时伴有非盘绕状脐血管的胎儿的围产期结局。
我们对缺乏脐血管盘绕的脐带进行了一项前瞻性研究。将围产期结局与出生时伴有盘绕状脐血管的新生儿的结局进行比较。
894例胎儿中有38例（4.3%）出生时伴有非盘绕状脐血管。非盘绕状组的宫内死亡发生率显著增加（P = 0.009）、早产发生率显著增加（P = 0.006）、产时反复出现胎儿心率减速（P < 0.00005）、因胎儿窘迫行手术分娩的发生率显著增加（P < 0.00005）、胎粪污染发生率显著增加（P = 0.007）以及解剖学-核型异常发生率显著增加（P = 0.03）。
我们的研究结果表明，伴有非盘绕状（即直的）脐血管的胎儿发生围产期发病和死亡的风险增加。非盘绕状脐血管可能代表一种使胎儿处于风险中的病理性发育过程。此外，正常盘绕状脐结构的缺失可能导致脐带在结构上抵抗外部压迫力的能力降低。
