家猫视网膜中水平细胞的拓扑结构。

Topography of horizontal cells in the retina of the domestic cat.

作者信息

Wässle H, Peichl L, Boycott B B

出版信息

Proc R Soc Lond B Biol Sci. 1978 Dec 18;203(1152):269-91. doi: 10.1098/rspb.1978.0105.

DOI:10.1098/rspb.1978.0105

Abstract

Neurofibrillar methods stain a class of horizontal cells in the cat retina which are shown to be identical with the A-type horizontal cell of Golgi-staining. Thus all of the A-type cells of a single retina can be observed. On this basis the changes in density and dendritic field size of A-type horizontal cells with respect to retinal eccentricity were measured. The decrease in density from centre to periphery is balanced by a corresponding increase in size of the dendritic field. Consequently each retinal point--independent of retinal position--is covered by the dendritic fields of three of four A-type horizontal cells. The nuclei and nucleoli of B-type horizontal cells could also be recognized in neurofibrillar-stained material and thus their distribution was determined. The density ratio B-type: A-type is 2.8 +/- 0.4 and does not vary much from the centre to the periphery of the retina. Each retinal point is also covered by four B-type horizontal cells. Thus a single cone can contact a maximum of eight horizontal cells. The rate of density decrease from centre to periphery is closely similar in cones and horizontal cells but greater in ganglion cells.

摘要

神经原纤维染色法可对猫视网膜中的一类水平细胞进行染色，结果显示这些细胞与经高尔基染色法显示的 A 型水平细胞相同。这样就能观察到单个视网膜中所有的 A 型细胞。在此基础上，测量了 A 型水平细胞的密度和树突野大小随视网膜离心率的变化。从中心到周边密度的降低被树突野大小相应的增加所平衡。因此，视网膜上的每个点——与视网膜位置无关——都被四个 A 型水平细胞中三个细胞的树突野所覆盖。在神经原纤维染色的材料中也能识别出 B 型水平细胞的细胞核和核仁，从而确定了它们的分布。B 型与 A 型的密度比为 2.8±0.4，从视网膜中心到周边变化不大。视网膜上的每个点也被四个 B 型水平细胞所覆盖。因此，单个视锥细胞最多可与八个水平细胞接触。视锥细胞和水平细胞从中心到周边的密度降低速率非常相似，但神经节细胞的降低速率更大。