胎儿贫血及其与腺苷浓度升高的关系。
Fetal anaemia and its relation with increased concentrations of adenosine.
作者信息
Ross Russell R I, Greenough A, Lagercrantz H, Dahlin I, Nicolaides K
机构信息
Department of Child Health, Kings College Hospital, London.
出版信息
Arch Dis Child. 1993 Jan;68(1 Spec No):35-6. doi: 10.1136/adc.68.1_spec_no.35.
Abstract
Adenosine concentrations were measured in umbilical venous blood obtained by cordocentesis from 14 fetuses of 19-34 weeks' gestation. The concentration did not change significantly with gestational age, but anaemic fetuses showed significantly increased concentrations of adenosine and there was a positive association with blood oxygen tension. These findings suggest that the fetus responds to tissue hypoxia by increasing blood adenosine concentrations from at least 19 weeks' gestation.
摘要
通过脐静脉穿刺从14例孕19 - 34周胎儿获取脐静脉血，测量其中腺苷浓度。该浓度并未随孕周显著变化，但贫血胎儿的腺苷浓度显著升高，且与血氧张力呈正相关。这些发现表明，至少从孕19周起，胎儿通过增加血液腺苷浓度来应对组织缺氧。
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