Barnett P S, Jones T A, McGregor A M, Banga J P, Sheer D
Department of Medicine, King's College School of Medicine and Dentistry, London, UK.
Cytogenet Cell Genet. 1993;62(4):188-9. doi: 10.1159/000133471.
Thyroid peroxidase (TPO), the enzyme responsible for thyroid hormone synthesis, is a key autoantigen in autoimmune thyroid disease. Based on the results of a study using both isotopic and nonisotopic in situ hybridization, we assign the gene coding for human TPO to chromosome region 2p25-->p24.
甲状腺过氧化物酶（TPO）是负责甲状腺激素合成的酶，是自身免疫性甲状腺疾病中的关键自身抗原。基于一项同时使用同位素和非同位素原位杂交的研究结果，我们将编码人TPO的基因定位于染色体区域2p25→p24。
