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Regional localization of the gene for thyroid peroxidase to human chromosome 2pter----p12.

作者信息

de Vijlder J J, Dinsart C, Libert F, Geurts van Kessel A, Bikker H, Bolhuis P A, Vassart G

机构信息

Academic Medical Center, University of Amsterdam, The Netherlands.

出版信息

Cytogenet Cell Genet. 1988;47(3):170-2. doi: 10.1159/000132538.

Abstract

A 2.0-kb thyroid peroxidase cDNA of human origin was used as probe for Southern blot hybridization of genomic DNA from human somatic cells and human-rodent somatic cell hybrids. The results showed that the gene coding for human thyroid peroxidase is located on chromosome. 2. Further analysis of hybrids derived from Burkitt lymphoma cells carrying a (2;8)(p12;q24) translocation revealed that the gene maps to the region 2pter----p12.

摘要

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