Tranchant C, Racamier E, Warter J M
Service de Neurologie II, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Eur Neurol. 1993;33(1):17-9. doi: 10.1159/000116892.
A 29-year-old woman developed a seronegative myasthenia gravis. A thorax CT scan demonstrated an anterior mediastinal mass. Thoracotomy showed a lymphofollicular thymic hyperplasia and Hodgkin's disease of the nodular sclerosing type with mediastinal lymph node localisation. This patient's brother had been suffering as well from Hodgkin's disease. Epidemiological similarities (genetic influences and the role of a viral agent) between Hodgkin's disease and myasthenia gravis and the immune abnormalities found in these two diseases suggest that their association is not fortuitous.
一名29岁女性患血清阴性重症肌无力。胸部CT扫描显示前纵隔肿块。开胸手术显示为淋巴滤泡性胸腺增生以及结节硬化型霍奇金病伴纵隔淋巴结受累。该患者的兄弟也曾患霍奇金病。霍奇金病与重症肌无力之间在流行病学方面的相似之处（遗传影响和病毒因子的作用）以及在这两种疾病中发现的免疫异常表明它们之间的关联并非偶然。
