Wium E T, Andersen B M, Flaegstad T
Barneavdelingen, Regionsykehuset i Tromsø.
Tidsskr Nor Laegeforen. 1993 Jan 30;113(3):329-33.
Haemophilus influenzae may cause serious infections, especially in small children. During the period 1980-90, 45 children with systemic H influenzae infections were admitted to the University Clinic, Tromsø. 17 patients had epiglottitis in the same period, but are not included in this material. One of the four septicemia patients and two of the 35 children with meningitis died, giving an overall lethality of 4.8%. Five of the patients with meningitis experienced neurological sequelae (14% of the patients with meningitis). Two of the systemic isolates of H influenzae were resistant to ampicillin because of beta-lactamase production, but all the isolates were susceptible to chloramphenicol and 3rd generation cephalosporins.
流感嗜血杆菌可能会引发严重感染,尤其是在幼儿中。在1980年至1990年期间,45名患有全身性流感嗜血杆菌感染的儿童被收治到特罗姆瑟大学诊所。同期有17名患者患有会厌炎,但未纳入本资料。4名败血症患者中有1名死亡,35名脑膜炎患儿中有2名死亡,总致死率为4.8%。5名脑膜炎患者出现了神经后遗症(占脑膜炎患者的14%)。有两株全身性流感嗜血杆菌分离株因产生β-内酰胺酶而对氨苄西林耐药,但所有分离株对氯霉素和第三代头孢菌素敏感。