Grossman H B, Sandler H M, Perez-Tamayo C
Department of Surgery, University of Michigan, Ann Arbor.
Urology. 1993 Mar;41(3):217-20. doi: 10.1016/0090-4295(93)90559-s.
A total of 7 patients with high grade, T3a (Stage B2) bladder cancer were treated with external radiation therapy and interstitial iridium implantation from May 1986 through March 1988. Follow-up has ranged from nineteen to sixty-one months with a median of forty months. One patient has required a cystectomy and is currently free of disease, and 1 patient has had recurrence of his cancer and metastatic carcinoma has developed; 5 are free of disease and have maintained their usual state of bladder function. Iridium implantation maintains bladder function and is effective therapy for selected individuals with localized, muscle-invading bladder cancer.
1986年5月至1988年3月期间，共有7例高级别T3a（B2期）膀胱癌患者接受了外照射治疗和铱近距离植入治疗。随访时间为19至61个月，中位随访时间为40个月。1例患者需要进行膀胱切除术，目前无疾病复发；1例患者癌症复发并已发展为转移性癌；5例患者无疾病复发，膀胱功能维持正常。铱植入可维持膀胱功能，是治疗局部肌肉浸润性膀胱癌患者的有效方法。
