Arnedo M, Gallo M, Agüero A, Molina F, Puerto A
Departamento Psicología Experimental y Fisiología del Comportamiento, Campus Universitario de Cartuja, Granada, Spain.
Behav Neural Biol. 1993 Jan;59(1):69-75. doi: 10.1016/0163-1047(93)91187-r.
The effect of medullary afferent vagal axotomy on NaCl-induced short-term and long-term taste aversion learning (TAL) was examined to assess the relevance of the vagus nerve in drug-induced TAL. The results show that medullary afferent vagal axotomy disrupts NaCl-induced short-term (nondelayed) TAL, while having no effect on learning acquired with the same product in long-term (delayed) TAL protocols. Acquisition of learning in delayed discrimination tasks may be mediated by alternative mechanisms of nonvagal nature, e.g., the humoral system. The possibility that short-term and long-term TAL may be mediated by different neurobiological substrates is discussed.
研究了延髓传入迷走神经切断术对氯化钠诱导的短期和长期味觉厌恶学习（TAL）的影响，以评估迷走神经在药物诱导的TAL中的相关性。结果表明，延髓传入迷走神经切断术会破坏氯化钠诱导的短期（非延迟）TAL，而对长期（延迟）TAL方案中使用相同产物获得的学习没有影响。延迟辨别任务中的学习获得可能由非迷走性质的替代机制介导，例如体液系统。文中讨论了短期和长期TAL可能由不同神经生物学底物介导的可能性。
