Agüero A, Arnedo M, Gallo M, Puerto A
Departamento de Psicología Experimental y Fisiología del Comportamiento, Universidad de Granada, Spain.
Pharmacol Biochem Behav. 1993 Aug;45(4):973-8. doi: 10.1016/0091-3057(93)90150-r.
Lesions to the lateral parabrachial nucleus (PBN), one of the subnuclei that make up the pontine parabrachial complex, impairs the acquisition of taste aversion learning (TAL) with LiCl as the toxic stimulus. In this experiment, PBNl-lesioned and control rats were trained to learn a delayed task with a 15-min interval between presentation of the gustatory and the aversive stimulus. The impairment in learning observed after lesions of the PBNl is discussed in terms of disruption of the transmission of toxic stimuli (LiCl) processed by the humoral pathway and the area postrema (AP).
外侧臂旁核（PBN）是构成脑桥臂旁复合体的亚核之一，对其损伤会损害以氯化锂作为毒性刺激的味觉厌恶学习（TAL）的获得。在本实验中，对PBNl损伤的大鼠和对照大鼠进行训练，使其学习一种延迟任务，味觉刺激和厌恶刺激之间的间隔为15分钟。根据体液途径和最后区（AP）处理的毒性刺激（氯化锂）传递的中断来讨论PBNl损伤后观察到的学习障碍。
