Jurfest-Ceccon M E, de Albuquerque Diniz E M, de Araujo-Ramos J L, Costa-Vaz F A
Departamento de Pediatría, Facultad de Medicina, Universidad de San Pablo, Brasil.
Bol Med Hosp Infant Mex. 1993 Mar;50(3):167-76.
A hundred twenty full term newborns infants (RN) with ABO or Rh isoimmunization who were submitted to exchange transfusion (ET) because hyperbilirubinemia have been studied and with the procedure were demonstrated: 1. Increase the levels of serum sodium in 2.8% in the RN of ABO group and 3.2% in the RN of Rh group with a recurrence of the original values prior to the procedure within three hours post-ET. 2. The levels of serum sodium equal or superior to 180 mEq/L (mmol/L) in the donor's blood led to hypernatremia after the ET, with a recurrence of the original values prior to the procedures within three hours post-ET. 3. The levels of serum potassium of the RN decreased (-7.7% in the ABO group and -5.47% in the Rh group) with a recurrence of the normal values in the control of six hours post-ET in the ABO group and one of 12 hours in the Rh group. 4. The levels of total calcium in the controls haven't been significantly altered up to 24 hours post-ET. 5. Regarding the pH, in spite of having used blood with low levels compared to those expected for fresh blood, the RN for this experiment maintained the acid-base balance within normal range. In relation to the hematimetric values, the ET: 1. Increase both hemoglobin (Hb) and hematocrit (Hto) values in both groups (increase of 5.6% in Hb and 6% in Hto in the ABO group and increase of 9.2% in Hb and 6.1% in Hto in the Rh group), right after the ET, with a reduction in the control posterior to that. 2. The values of Hb and Hto were always inferior in the RN in the Rh group. Therefore, it has been shown the high intensity of the hemolysis in this group.
对120名因高胆红素血症接受换血治疗（ET）的ABO或Rh血型同种免疫的足月儿进行了研究，该治疗过程显示：1. ABO组足月儿血清钠水平升高2.8%，Rh组足月儿血清钠水平升高3.2%，换血后3小时内恢复至治疗前的原始值。2. 供体血液中血清钠水平等于或高于180 mEq/L（mmol/L）导致换血后高钠血症，换血后3小时内恢复至治疗前的原始值。3. 足月儿的血清钾水平下降（ABO组下降7.7%，Rh组下降5.47%），ABO组换血后6小时恢复正常，Rh组换血后12小时恢复正常。4. 直至换血后24小时，对照组的总钙水平未发生显著变化。5. 关于pH值，尽管使用的血液水平低于新鲜血液预期水平，但本实验中的足月儿仍将酸碱平衡维持在正常范围内。关于血液学指标，换血治疗：1. 两组的血红蛋白（Hb）和血细胞比容（Hto）值均升高（ABO组Hb升高5.6%，Hto升高6%；Rh组Hb升高9.2%，Hto升高6.1%），换血后立即升高，之后对照组下降。2. Rh组足月儿的Hb和Hto值始终较低。因此，该组显示出高强度的溶血。
