Matthew E B, Holstrom F M, Kaspar R L
Crit Care Med. 1977 Mar-Apr;5(2):76-81. doi: 10.1097/00003246-197703000-00003.
A safe, simple, reliable technique for sampling uncontaminated peripheral bronchial secretions in patients with endotracheal tubes has been developed. It is easily performed and requires no special training or equipment. This report summarizes the techniques's usefulness in providing diagnostic samples of peripheral airway secretions from 20 patients with pneumonic infiltrates. In eight of the patients, a single organism was recovered from the peripheral airway despite polymicrobial colonization of the upper airways. An additional patient had two anaerobes. The recovered organism's role as a pathogen was verified by an appropriate response to specific antibiotic therapy in two patients, isolation from blood or empyema fluid in five, confirmation by bronchoscopy in one, and transtracheal aspiration after extubation in one. Peripheral bronchial secretions were sterile in the remaining 11 patients, even though multiple organsims were isolated from usual tracheal suctionings.
已开发出一种用于对气管插管患者采集未受污染的外周支气管分泌物的安全、简单、可靠技术。该技术操作简便,无需特殊培训或设备。本报告总结了该技术在为20例有肺炎浸润患者提供外周气道分泌物诊断样本方面的效用。在8例患者中,尽管上呼吸道存在多种微生物定植,但外周气道中分离出单一微生物。另有1例患者分离出两种厌氧菌。在2例患者中,通过对特定抗生素治疗的适当反应证实了所分离微生物作为病原体的作用,5例通过血或脓胸液分离,1例通过支气管镜检查证实,1例在拔管后经气管抽吸证实。其余11例患者外周支气管分泌物无菌,尽管从常规气管抽吸物中分离出多种微生物。