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新型心脏选择性β-肾上腺素能阻滞剂醋丁洛尔(Bay c 7705)的抗心律失常特性:初步报告

Anti-arrhythmic properties of acebutolol (Bay c 7705), a new cardioselective beta-adrenergic blocking agent: a preliminary report.

作者信息

Burckhardt K, Raeder E, Ebner F

出版信息

Curr Med Res Opin. 1977;4(7):496-500. doi: 10.1185/03007997709109339.

Abstract

A study was carried out in 20 ambulatory patients with various heart diseases and different forms of cardiac arrhythmias to evaluate the anti-arrhythmic effect of acebutolol when given orally(400 mg/day). Long-term(4 hour) ECGs were monitored before and after 3 days of treatment. The results showed that after acebutolol treatment 60% of all the arrhythmias were prevented or abolised, 16% were improved, and only 24% persisted unchanged.

摘要

对20名患有各种心脏病和不同形式心律失常的门诊患者进行了一项研究,以评估口服醋丁洛尔(400毫克/天)时的抗心律失常效果。在治疗3天前后监测长期(4小时)心电图。结果显示,醋丁洛尔治疗后,所有心律失常中有60%得到预防或消除,16%有所改善,只有24%保持不变。

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