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Synovial copper deposition as a possible explanation of arthropathy in Wilson's disease.

作者信息

Kramer U, Weinberger A, Yarom R, Zoldan J, Bahar A, Godoth N

机构信息

Department of Internal Medicine B, Beilinson Medical Center, Petah Tiqva, Israel.

出版信息

Bull Hosp Jt Dis. 1993 Winter;52(2):46-9.

PMID:8443556
Abstract

A patient with longstanding Wilson's disease and arthritis is presented. Synovial biopsy disclosed thickening of the membrane, intimal histiocytes, and lymphocyte infiltration without pigmentation. X-ray energy spectroscopy demonstrated copper and iron in high concentrations. These findings may contribute to our understanding of the development of the arthropathy in patients with Wilson's disease.

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