Spácil J, Petrásek J, Ceska R, Sobra J
III. interní klinika 1. LF UK, FN 2 s fakultní poliklinikou, Praha, Ceská republika.
Cor Vasa. 1993;35(1):27-31.
Using sonography, the common carotid artery was examined in patients with hyperlipoproteinaemia and in controls. In 21 controls, the intima was present in 62%, intimal thickness was 0.41 +/- 0.14 mm. In patients with familial hypercholesterolaemia free of ischaemic heart disease (46 patients), the intima was demonstrable in 89%, intimal thickness was 0.74 +/- 0.21 mm. In patients with ischaemic heart disease (19 patients), the intima could be demonstrated in 100%, its thickness was 0.84 +/- 0.31 mm. In 21 patients with familial combined hyperlipoproteinaemia, the intima was present in 90%, intimal thickness was 0.73 +/- 0.17 mm. Intimal thickness was significantly greater (p < 0.001) in all groups of patients with hyperlipoproteinaemia than in the control group. A significant correlation between cholesterol levels and intimal thickness (p < 0.01) was demonstrated.
采用超声检查高脂血症患者及对照组的颈总动脉。在21名对照组中,62%可见内膜,内膜厚度为0.41±0.14毫米。在无缺血性心脏病的家族性高胆固醇血症患者(46例)中,89%可见内膜,内膜厚度为0.74±0.21毫米。在缺血性心脏病患者(19例)中,100%可显示内膜,其厚度为0.84±0.31毫米。在21例家族性混合性高脂血症患者中,90%可见内膜,内膜厚度为0.73±0.17毫米。所有高脂血症患者组的内膜厚度均显著大于对照组(p<0.001)。胆固醇水平与内膜厚度之间存在显著相关性(p<0.01)。