接受原位肝移植患者的肝炎病毒标志物
Hepatitis viral markers in patients undergoing primary liver transplants.
作者信息
Lewis J H, el-Ashmawy L, Ramsey G E, Bontempo F A, Rochlani M, Demetris A J, Van Thiel D H, Starzl T E
机构信息
Central Blood Bank, Pittsburgh, Pennsylvania 15219.
出版信息
Dig Dis Sci. 1993 Mar;38(3):457-61. doi: 10.1007/BF01316499.
The purpose of the study was to determine the prevalence in liver transplant (OLTx) patients of the hepatitis markers (anti-A, anti-B, anti-C, anti-D and HBsAg) and the interrelationships between markers and patients' sexes, ages, dates of transplant, clinicopathological diagnoses, and short-term survivals. Slightly more than half of the patients were male. Anti-A and anti-B were about evenly distributed between male and female. Anti-C, anti-D, and HBsAg were far more common in males. Age and year of transplant showed only a moderate increase in anti-A with increasing age. Anti-A was found in 57% of all patients, anti-B in 18%, anti-C in 17%, and HBsAg in 17%. Anti-D was tested only in patients who were positive for anti-B or HBsAg and occurred in 21 (11%) of 185. The poorest short-term survival occurred in males who showed both anti-A and HBsAg.
本研究的目的是确定肝移植（OLTx）患者中肝炎标志物（抗A、抗B、抗C、抗D和HBsAg）的流行情况，以及标志物与患者性别、年龄、移植日期、临床病理诊断和短期生存率之间的相互关系。略超过一半的患者为男性。抗A和抗B在男性和女性之间分布大致均匀。抗C、抗D和HBsAg在男性中更为常见。年龄和移植年份显示，随着年龄的增长，抗A仅略有增加。在所有患者中，57%的患者检测到抗A，18%检测到抗B，17%检测到抗C，17%检测到HBsAg。仅对抗B或HBsAg呈阳性的患者进行抗D检测，185例患者中有21例（11%）检测到抗D。抗A和HBsAg均呈阳性的男性短期生存率最差。
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