Kühböck J, Pehamberger H, Mach K, Diem E, Kokoschka E M, Pötzi P
Wien Klin Wochenschr. 1978 Dec 22;90(24):856-8.
24 patients with metastatic malignant melanoma were treated with DTIC applied alone or in combination with other cytotoxic agents (Oncovin, Bleomycin, Adriblastin). Treatment resulted in objective improvement (3 patients), subjective improvement (2 patients), stable state (5 patients). The other patients showed further progression of their disease.
24例转移性恶性黑色素瘤患者接受了单独使用达卡巴嗪(DTIC)或与其他细胞毒性药物(长春新碱、博来霉素、阿霉素)联合使用的治疗。治疗产生了客观改善(3例患者)、主观改善(2例患者)、病情稳定(5例患者)。其他患者病情进一步进展。