Risk factors for secondary depression among Mexican Americans and non-Hispanic whites. Alcohol use, alcohol dependence, and reasons for drinking.

We evaluated demographic (age, gender, income), cultural (ethnicity, acculturation), clinical (alcohol use, alcohol dependence), and motivational (subjective reasons for drinking) potential risk factors for secondary depression in 372 persons with lifetime alcohol abuse or dependence (from a randomly selected community sample of 2393). Lifetime alcohol abuse or dependence increased the risk of major depression by a factor of approximately 2 to 7. Recent secondary depression was present in 2% to 18% of persons meeting criteria for alcohol use disorders. Low income, female gender, and among Mexican Americans, low acculturation were associated with increased risk of secondary depression. Persons with lifetime alcohol diagnoses who currently drank, but did not name relaxation as a reason for drinking, were also at higher risk for secondary depression. Drinking to forget was associated with increased risk of secondary depression among Mexican American alcoholics, but not among non-Hispanic white alcoholics. Current abstinence was associated with greater risk among lifetime alcoholics born in Mexico, but not among those born in the United States.