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家鼠中导致核型变异的自发罗伯逊融合——亚洲的首例报告

Spontaneour Robertsonian fusion leading to karyotype variation in the house mouse - first report form Asia.

作者信息

Chakrabarti S, Chakrabarti A

出版信息

Experientia. 1977 Feb 15;33(2):175-7. doi: 10.1007/BF02124050.

Abstract

The occurrence of spontaneous Robertsonian fusion leading to 2n=39 chromosomes (NF=40) in the house mouse (Mus musculus domesticus) has been reported for the first time from Asia. 3 phenotypically normal female mice collected from 2 distantly located populations of India (Tripura and Calcutta) show centric fusion in somatic chromosomes between pairs 2 and 16, and 8 and 14 respectively. C-banding analysis revealed that the (sub)metacentric has been originated by fusion between the broken/eroded centromeres of 2 telocentric chromosomes.

摘要

在家鼠(小家鼠指名亚种)中首次在亚洲报道了自发罗伯逊融合导致2n = 39条染色体(NF = 40)的情况。从印度两个地理位置相距甚远的种群(特里普拉和加尔各答)收集的3只表型正常的雌性小鼠,其体细胞染色体中分别显示出第2对和第16对、第8对和第14对之间的着丝粒融合。C带分析表明,(亚)中着丝粒染色体是由两条端着丝粒染色体断裂/侵蚀的着丝粒之间的融合产生的。

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