涎腺切除大鼠发生口腔念珠菌病。

Oral candidiasis established in the sialoadenectomised rat.

作者信息

Jorge A O, Totti M A, de Almeida O P, Scully C

机构信息

Department of Oral Pathology, Faculty of Dentistry, Piracicaba-SP, Brasil.

出版信息

J Oral Pathol Med. 1993 Feb;22(2):54-6. doi: 10.1111/j.1600-0714.1993.tb00042.x.

DOI:10.1111/j.1600-0714.1993.tb00042.x

PMID:8445543

Abstract

Xerostomia provoked in rats by surgical removal of the major salivary glands favoured the development of oral candidiasis. After 32 weeks of inoculation, 20% of normal and 70% of xerostomic rats showed candidal infection on the tongue but only in xerostomic rats did candidiasis affect the pharyngeal aspect of the tongue.

摘要

通过手术切除大鼠主要唾液腺引发的口腔干燥症有利于口腔念珠菌病的发展。接种32周后，20%的正常大鼠和70%的口腔干燥大鼠的舌头出现念珠菌感染，但只有口腔干燥大鼠的念珠菌病会影响舌的咽部。