Elangbam C S, Qualls C W, Ewing S A, Lochmiller R L
Department of Veterinary Pathology, College of Veterinary Medicine, Stillwater, Oklahoma 74078.
J Wildl Dis. 1993 Jan;29(1):161-4. doi: 10.7589/0090-3558-29.1.161.
Cryptosporidiosis, previously unreported in cotton rats (Sigmodon hispidus), was observed in one of nine cotton rats from Pryor, Oklahoma (USA). Infection was confined to the large intestine. Microscopically, numerous cryptosporidians measuring 2 to 3 microns in diameter were intimately associated with the luminal surface of colonic and rectal mucosae. The affected lamina propria of the large intestine was diffusely infiltrated by eosinophils, lymphocytes and macrophages. Ultrastructurally, numerous trophozoites and a single schizont were observed. Microvilli were displaced by the presence of cryptosporidians at the attachment site.
隐孢子虫病在以前的棉鼠（刚毛囊鼠）中未曾有过报道，在美国俄克拉荷马州普赖尔市的9只棉鼠中，有1只被观察到感染了隐孢子虫病。感染局限于大肠。在显微镜下，大量直径为2至3微米的隐孢子虫与结肠和直肠黏膜的腔面紧密相连。受影响的大肠固有层被嗜酸性粒细胞、淋巴细胞和巨噬细胞弥漫性浸润。在超微结构上，观察到大量滋养体和单个裂殖体。在附着部位，隐孢子虫的存在使微绒毛移位。
